Configuring the backup job for BizTalk is a fairly simple task, while restoring it is a bit more complicated. By default the BizTalk backup job makes a full backup once a day, and a log backup every 15 minutes. When backups are done,
a mark is set on each file. This mark is the same across all databases, and should be used to restore all databases to the same point in time and keeping all databases in a consistent state.
The BizTalk Database Restore cmdlets
will make the process much easier.
For more information: